Ac-Di-Sol®

Croscarmellose Sodium NF, Ph. Eur., JP
The superior disintegrant
 
Introducing Ac-Di-Sol® Croscarmellose Sodium, a highly regarded offering by IFF designed for pharmaceutical manufacturers. As an internally cross-linked sodium carboxymethyl cellulose (NaCMC), this product plays a crucial role in enhancing the disintegration and drug dissolution of various pharmaceutical forms like tablets, capsules, and granules.
 
Ac-Di-Sol® superdisintegrant excels at promoting rapid disintegration and drug dissolution with minimal usage in tablets, capsules, granules, and similar rapidly disintegrating dosage forms. Ac-Di-Sol® is renowned for its exceptional quality, consistency, and stability.
 
Ac-Di-Sol® SDW-802 Croscarmellose Sodium, a non-GMO superdisintegrant, is derived from wood pulp and represents a specialized grade of croscarmellose sodium. The choice of cellulose source significantly influences the effectiveness of a disintegrant by impacting its wicking and swelling properties. Through meticulous optimization of morphology and manufacturing processes, Ac-Di-Sol® SDW-802 delivers comparable disintegration performance to Ac-Di-Sol® SD-711 (which uses cotton-based material).
 
Key Features:
1. Superior Performance: Enables faster disintegration and dissolution compared to competitors, even at lower usage levels (1-2%), due to excellent water uptake and rapid swelling properties.
2. Broad Functionality: Compatible with various manufacturing processes such as direct compression, dry and wet granulation, and continuous manufacturing. It seamlessly supports different dosage forms, including tablets, capsules, and granules.
3. Purity: Boasts consistent critical material attributes, including fibrous morphology, low moisture content, minimal impurities, and low water-soluble content. These qualities ensure robust and dependable performance.
 
Choose Ac-Di-Sol® Croscarmellose Sodium for exceptional disintegration performance with enhanced reliability and versatility across pharmaceutical formulations.