Avicel® PH (MCC)
Microcrystalline Cellulose, NF, Ph. Eur., JP
Microcrystalline cellulose that enables easier processing, improved physical properties of tablets, and streamlined filling of capsules for more robust products. The introduction of Avicel PH was a catalyst for the pharmaceutical industry’s conversion to direct compression tablet technology, creating new levels of manufacturing efficiency. Today’s Avicel PH continues to set new standards, with enhanced grades designed to boost productivity and meet any formulation challenge.
Generic and alternative names
- Avicel® PH Microcrystalline cellulose (MCC)
- Chemical Name: 4-O-[(1S)-hexopyranosyl]-D-glycero-hexopyranose
Claims / benefits / efficacy
- Improved powder flow
- Optimum granule properties
- Robust high shear wet granulation process
- Improve tablet compression profile
- Uniform tablet content
- Increased batch size
- Reduced moisture-related API degradation
Function
- Filler
- Diluent
Application
- Direct compression tableting
- Wet granulation
- Extrusion and spheronization
- Dry granulation roller compaction
Grades
Available Grades Particle Size, μm Moisture, % Differentiating Features Avicel® PH-101 50 3.0 to 5.0 Wet Granulation Avicel® PH-102 100 3.0 to 5.0 Direct Compression Avicel® PH-105 20 NMT 5.0 Superior Compactability Avicel® PH-102 SCG 150 3.0 to 5.0 Superior Flow Avicel® PH-200 180 2.0 to 5.0 Superior Flow Avicel® PH-301 50 3.0 to 5.0 High Density Avicel® PH-302 100 3.0 to 5.0 High Density Avicel® PH-103 50 NMT 3 Low Moisture Avicel® PH-113 50 NMT 2 Low Moisture Avicel® PH-112 100 NMT 1.5 Low Moisture Avicel® PH-200 LM 180 NMT 1.5 Low Moisture